Re-structuring lentiviral vectors to express genomic RNA via cap-dependent translation

Lentiviral (LV) vectors based on human immunodeficiency virus type I (HIV-1) package two copies of their single-stranded RNA into vector particles. Normally, this RNA genome is reverse transcribed into a double-stranded DNA provirus that integrates into the cell genome, providing permanent gene tran...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Counsell, John R., De Brabandere, Guillaume, Karda, Rajvinder, Moore, Marc, Greco, Antonio, Bray, Alysha, Diaz, Juan Antinao, Perocheau, Dany P., Mock, Ulrike, Waddington, Simon N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838728/
https://ncbi.nlm.nih.gov/pubmed/33553484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.12.005
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