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Coordinate enhancement of transgene transcription and translation in a lentiviral vector

BACKGROUND: Coordinate enhancement of transgene transcription and translation would be a potent approach to significantly improve protein output in a broad array of viral vectors and nonviral expression systems. Many vector transgenes are complementary DNA (cDNA). The lack of splicing can significan...

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Main Authors: Yilmaz, Alper, Fernandez, Soledad, Lairmore, Michael D, Boris-Lawrie, Kathleen
格式: Artigo
語言:Inglês
出版: BioMed Central 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1388234/
https://ncbi.nlm.nih.gov/pubmed/16480517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-13
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