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Enhancement of Drug Sensitivity by Knockdown of HIF-1α in Gastric Carcinoma Cells

In this study, the effects of hypoxia-inducible factor-1α (HIF-1α) on gastric carcinoma (GC) drug resistance through apoptosis-related genes are investigated. First, HIF-1α-specific siRNA was synthetized and transfected into drug-resistant GC cell line OCUM-2MD3/L-OHP. Then MTT assay was applied to...

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Detalhes bibliográficos
Publicado no:Oncol Res
Main Authors: Zhao, Qun, Tan, Bi-Bo, Li, Yong, Fan, Li-Qiao, Yang, Pei-Gang, Tian, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838699/
https://ncbi.nlm.nih.gov/pubmed/26931435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504015X14500513118029
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