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HIF-1α Induces Multidrug Resistance in Gastric Cancer Cells by Inducing MiR-27a

This study aimed to determine the correlation between HIF-1α and miR-27a expression and to evaluate the effect of inhibition of HIF-1α expression on miR-27a expression and drug resistance in gastric cancer (GC). In the present study, real time-PCR and Western blot were performed to detect the expres...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zhao, Qun, Li, Yong, Tan, Bi-bo, Fan, Li-qiao, Yang, Pei-gang, Tian, Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546344/
https://ncbi.nlm.nih.gov/pubmed/26292288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132746
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