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IGF-I Induces Epithelial-to-Mesenchymal Transition via the IGF-IR–Src–MicroRNA-30a–E-Cadherin Pathway in Nasopharyngeal Carcinoma Cells

Recurrence and distant metastasis are the most common cause of therapeutic failure in nasopharyngeal carcinoma (NPC) patients. Insulin-like growth factor I (IGF-I) can induce epithelial-to-mesenchymal transition (EMT) in many epithelial tumors; however, whether IGF-I can enhance NPC metastasis by EM...

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Detalhes bibliográficos
Publicado no:Oncol Res
Main Authors: Wang, Ruoyu, Li, Heming, Guo, Xuefen, Wang, Zhe, Liang, Shanshan, Dang, Chengxue
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838631/
https://ncbi.nlm.nih.gov/pubmed/27656832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504016X14648701447931
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