Antenatal Endotoxin Impairs Lung Mechanics and Increases Sensitivity to Ventilator-Induced Lung Injury in Newborn Rat Pups

Perinatal inflammation due to chorioamnionitis and ventilator-induced lung injury (VILI) at birth is independent risk factors for the development of bronchopulmonary dysplasia (BPD). We have previously shown that antenatal endotoxin (ETX) causes abnormal lung structure and function in 2-week-old rat...

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Publicat a:Front Physiol
Autors principals: Mandell, Erica W., Mattson, Courtney, Seedorf, Gregory, Ryan, Sharon, Gonzalez, Tania, Wallbank, Alison, Bye, Elisa M., Abman, Steven H., Smith, Bradford J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838561/
https://ncbi.nlm.nih.gov/pubmed/33519519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.614283
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