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HIF-1 Dimerization Inhibitor Acriflavine Enhances Antitumor Activity of Sunitinib in Breast Cancer Model

Antiangiogenic therapy is a promising strategy for cancer therapy. However, antiangiogenic therapy can induce intratumor hypoxia and hypoxia-inducible factor-1 (HIF-1) expression, which slows cancer progression. In our present study, we found that antiangiogenic therapy with sunitinib plus HIF-1 dim...

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Detalhes bibliográficos
Publicado no:Oncol Res
Main Authors: Yin, Tao, He, Sisi, Shen, Guobo, Wang, Yongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838425/
https://ncbi.nlm.nih.gov/pubmed/26168132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504014X13983417587366
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