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Restoration of Cardiac Function After Myocardial Infarction by Long-Term Activation of the CNS Leptin-Melanocortin System

Heart failure has a high mortality rate, and current therapies offer limited benefits. The authors demonstrate that activation of the central nervous system leptin-melanocortin pathway confers remarkable protection against progressive heart failure following severe myocardial infarction. The benefic...

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Bibliographic Details
Published in:JACC Basic Transl Sci
Main Authors: Gava, Fabio N., da Silva, Alexandre A., Dai, Xuemei, Harmancey, Romain, Ashraf, Sadia, Omoto, Ana C.M., Salgado, Mateus C., Moak, Sydney P., Li, Xuan, Hall, John E., do Carmo, Jussara M.
Format: Artigo
Language:Inglês
Published: Elsevier 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838051/
https://ncbi.nlm.nih.gov/pubmed/33532666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.11.007
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