A Functional Melanocortin System May Be Required for Chronic CNS-Mediated Antidiabetic and Cardiovascular Actions of Leptin

OBJECTIVE: We recently showed that leptin has powerful central nervous system (CNS)-mediated antidiabetic and cardiovascular actions. This study tested whether the CNS melanocortin system mediates these actions of leptin in diabetic rats. RESEARCH DESIGN AND METHODS: A cannula was placed in the late...

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Bibliografiske detaljer
Main Authors: da Silva, Alexandre A., do Carmo, Jussara M., Freeman, J. Nathan, Tallam, Lakshmi S., Hall, John E.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2009
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712780/
https://ncbi.nlm.nih.gov/pubmed/19491210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1221
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