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HIV-1 and HIV-1-Tat Induce Mitochondrial DNA Damage in Human Neurons

INTRODUCTION: Mitochondrial dysregulation is a key event in HIV-1 infection. Recent studies have suggested that age-related neurodegenerative disorders are associated with increased mitochondrial DNA (mtDNA) damage. As accelerated ageing was found in HIV-1 patients, we hypothesized that HIV-1 infect...

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Dettagli Bibliografici
Pubblicato in:J HIV AIDS
Autori principali: Darbinian, Nune, Darbinyan, Armine, Merabova, Nana, Selzer, Michael E, Amini, Shohreh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837619/
https://ncbi.nlm.nih.gov/pubmed/33506104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.16966/2380-5536.176
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