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HIV-1 Tat Inhibits NGF-Induced Egr-1 Transcriptional Activity and Consequent p35 Expression in Neural Cells

Infection with HIV-1 causes degeneration of neurons leading to motor and cognitive dysfunction in AIDS patients. One of the key viral regulatory proteins, Tat, which is released by infected cells, can be taken up by various uninfected cells including neurons and by dysregulating several biological e...

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Detaylı Bibliyografya
Asıl Yazarlar: DARBINIAN, NUNE, DARBINYAN, ARMINE, CZERNIK, MARTA, PERUZZI, FRANCESCA, KHALILI, KAMEL, REISS, KRZYSZTOF, GORDON, JENNIFER, AMINI, SHOHREH
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712724/
https://ncbi.nlm.nih.gov/pubmed/18247371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21382
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