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HIV-1 Tat Inhibits NGF-Induced Egr-1 Transcriptional Activity and Consequent p35 Expression in Neural Cells
Infection with HIV-1 causes degeneration of neurons leading to motor and cognitive dysfunction in AIDS patients. One of the key viral regulatory proteins, Tat, which is released by infected cells, can be taken up by various uninfected cells including neurons and by dysregulating several biological e...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712724/ https://ncbi.nlm.nih.gov/pubmed/18247371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21382 |
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