Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis

Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...

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Vydáno v:PLoS Biol
Hlavní autoři: Sterkel, Marcos, Haines, Lee R., Casas-Sánchez, Aitor, Owino Adung’a, Vincent, Vionette-Amaral, Raquel J., Quek, Shannon, Rose, Clair, Silva dos Santos, Mariana, García Escude, Natalia, Ismail, Hanafy M., Paine, Mark I., Barribeau, Seth M., Wagstaff, Simon, MacRae, James I., Masiga, Daniel, Yakob, Laith, Oliveira, Pedro L., Acosta-Serrano, Álvaro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837477/
https://ncbi.nlm.nih.gov/pubmed/33497373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000796
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