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LILRB4 Expression in Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome Based on Response to Hypomethylating Agents

LILRB4 is expressed on AML M4/M5 cells and negatively regulates immune cell activation via T cell suppression. Its expression and role in CMML and MDS are unknown. We investigated LILRB4 expression in 19 CMML and 27 MDS patients and correlated it with response to subsequent HMA therapy. LILRB4 RNA e...

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Dades bibliogràfiques
Publicat a:Leuk Lymphoma
Autors principals: Chien, Kelly S., Class, Caleb A., Montalban-Bravo, Guillermo, Wei, Yue, Sasaki, Koji, Naqvi, Kiran, Ganan-Gomez, Irene, Yang, Hui, Soltysiak, Kelly A., Kanagal-Shamanna, Rashmi, Do, Kim-Anh, Kantarjian, Hagop M., Garcia-Manero, Guillermo
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836710/
https://ncbi.nlm.nih.gov/pubmed/32036728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2020.1723014
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