Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis and cytopenias due to uncontrolled programmed cell death. The presence of pro-inflammatory cytokines and constitutive activation of innate immunity signals in MDS cells suggest inflammatory cell death, such as necroptosis...

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Publicado en:Leukemia
Main Authors: Montalban-Bravo, Guillermo, Class, Caleb A., Ganan-Gomez, Irene, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Richard-Carpentier, Guillaume, Naqvi, Kiran, Wei, Yue, Yang, Hui, Soltysiak, Kelly A., Chien, Kelly, Bueso-Ramos, Carlos, Do, Kim-Anh, Kantarjian, Hagop, Garcia-Manero, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056563/
https://ncbi.nlm.nih.gov/pubmed/31719677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0623-5
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