Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis and cytopenias due to uncontrolled programmed cell death. The presence of pro-inflammatory cytokines and constitutive activation of innate immunity signals in MDS cells suggest inflammatory cell death, such as necroptosis...

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Dettagli Bibliografici
Pubblicato in:Leukemia
Autori principali: Montalban-Bravo, Guillermo, Class, Caleb A., Ganan-Gomez, Irene, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Richard-Carpentier, Guillaume, Naqvi, Kiran, Wei, Yue, Yang, Hui, Soltysiak, Kelly A., Chien, Kelly, Bueso-Ramos, Carlos, Do, Kim-Anh, Kantarjian, Hagop, Garcia-Manero, Guillermo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056563/
https://ncbi.nlm.nih.gov/pubmed/31719677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0623-5
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