Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis and cytopenias due to uncontrolled programmed cell death. The presence of pro-inflammatory cytokines and constitutive activation of innate immunity signals in MDS cells suggest inflammatory cell death, such as necroptosis...

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Vydáno v:Leukemia
Hlavní autoři: Montalban-Bravo, Guillermo, Class, Caleb A., Ganan-Gomez, Irene, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Richard-Carpentier, Guillaume, Naqvi, Kiran, Wei, Yue, Yang, Hui, Soltysiak, Kelly A., Chien, Kelly, Bueso-Ramos, Carlos, Do, Kim-Anh, Kantarjian, Hagop, Garcia-Manero, Guillermo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056563/
https://ncbi.nlm.nih.gov/pubmed/31719677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0623-5
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