Co‐administration of 2’3’-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model

Persistent infection with high-risk genotypes of human papillomavirus (HPV) is the leading cause of cervical cancer. The HPV oncoprotein E7 is constitutively expressed in cervical cancer and considered as an essential target for tumor-specific immunity. The goal of this study was to develop a candid...

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Detalhes bibliográficos
Publicado no:Infect Agent Cancer
Main Authors: Dorostkar, Fariba, Arashkia, Arash, Roohvand, Farzin, Shoja, Zabihollah, Navari, Mohsen, Mashhadi Abolghasem Shirazi, Maryam, Shahosseini, Zahra, Farahmand, Mohammad, Shams nosrati, Mohammad Sadegh, Jalilvand, Somayeh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836183/
https://ncbi.nlm.nih.gov/pubmed/33499895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-021-00346-7
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