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Protein-coding repeat polymorphisms strongly shape diverse human phenotypes

Hundreds of the proteins encoded in human genomes contain domains that vary in size or copy number due to variable numbers of tandem repeats (VNTRs) in protein-coding exons. VNTRs have eluded analysis by the molecular methods-SNP arrays and high-throughput sequencing-used in large-scale human geneti...

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Dades bibliogràfiques
Publicat a:bioRxiv
Autors principals: Mukamel, Ronen E, Handsaker, Robert E, Sherman, Maxwell A, Barton, Alison R, Zheng, Yiming, McCarroll, Steven A, Loh, Po-Ru
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836119/
https://ncbi.nlm.nih.gov/pubmed/33501449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.19.427332
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