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Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients’ Brain in a Dish

Mitochondrial diseases are a heterogeneous group of rare genetic disorders that can be caused by mutations in nuclear (nDNA) or mitochondrial DNA (mtDNA). Mutations in mtDNA are associated with several maternally inherited genetic diseases, with mitochondrial dysfunction as a main pathological featu...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Povea-Cabello, Suleva, Villanueva-Paz, Marina, Suárez-Rivero, Juan M., Álvarez-Córdoba, Mónica, Villalón-García, Irene, Talaverón-Rey, Marta, Suárez-Carrillo, Alejandra, Munuera-Cabeza, Manuel, Sánchez-Alcázar, José A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835939/
https://ncbi.nlm.nih.gov/pubmed/33510772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.610764
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