Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients’ Brain in a Dish

Mitochondrial diseases are a heterogeneous group of rare genetic disorders that can be caused by mutations in nuclear (nDNA) or mitochondrial DNA (mtDNA). Mutations in mtDNA are associated with several maternally inherited genetic diseases, with mitochondrial dysfunction as a main pathological featu...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Povea-Cabello, Suleva, Villanueva-Paz, Marina, Suárez-Rivero, Juan M., Álvarez-Córdoba, Mónica, Villalón-García, Irene, Talaverón-Rey, Marta, Suárez-Carrillo, Alejandra, Munuera-Cabeza, Manuel, Sánchez-Alcázar, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835939/
https://ncbi.nlm.nih.gov/pubmed/33510772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.610764
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