Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients’ Brain in a Dish

Mitochondrial diseases are a heterogeneous group of rare genetic disorders that can be caused by mutations in nuclear (nDNA) or mitochondrial DNA (mtDNA). Mutations in mtDNA are associated with several maternally inherited genetic diseases, with mitochondrial dysfunction as a main pathological featu...

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Библиографические подробности
Опубликовано в: :Front Genet
Главные авторы: Povea-Cabello, Suleva, Villanueva-Paz, Marina, Suárez-Rivero, Juan M., Álvarez-Córdoba, Mónica, Villalón-García, Irene, Talaverón-Rey, Marta, Suárez-Carrillo, Alejandra, Munuera-Cabeza, Manuel, Sánchez-Alcázar, José A.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Genetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835939/
https://ncbi.nlm.nih.gov/pubmed/33510772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.610764
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