Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients’ Brain in a Dish

Mitochondrial diseases are a heterogeneous group of rare genetic disorders that can be caused by mutations in nuclear (nDNA) or mitochondrial DNA (mtDNA). Mutations in mtDNA are associated with several maternally inherited genetic diseases, with mitochondrial dysfunction as a main pathological featu...

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Dettagli Bibliografici
Pubblicato in:Front Genet
Autori principali: Povea-Cabello, Suleva, Villanueva-Paz, Marina, Suárez-Rivero, Juan M., Álvarez-Córdoba, Mónica, Villalón-García, Irene, Talaverón-Rey, Marta, Suárez-Carrillo, Alejandra, Munuera-Cabeza, Manuel, Sánchez-Alcázar, José A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835939/
https://ncbi.nlm.nih.gov/pubmed/33510772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.610764
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