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pH-Induced Local Unfolding of the Phl p 6 Pollen Allergen From cpH-MD
Susceptibility to endosomal degradation is a decisive contribution to a protein's immunogenicity. It is assumed that the processing kinetics of structured proteins are inherently linked to their probability of local unfolding. In this study, we quantify the impact of endosomal acidification on...
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| Publicat a: | Front Mol Biosci |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7835895/ https://ncbi.nlm.nih.gov/pubmed/33511157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.603644 |
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