Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers

SIMPLE SUMMARY: Pyruvate kinase muscle type (PKM) is a key enzyme in glycolysis and is a mediator of the Warburg effect in tumors. The association of PKM with survival of cancer patients is controversial. In this study, we investigated the associations of the alternatively spliced transcripts of PKM...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Li, Xiangyu, Kim, Woonghee, Arif, Muhammad, Gao, Chunxia, Hober, Andreas, Kotol, David, Strandberg, Linnéa, Forsström, Björn, Sivertsson, Åsa, Oksvold, Per, Turkez, Hasan, Grøtli, Morten, Sato, Yusuke, Kume, Haruki, Ogawa, Seishi, Boren, Jan, Nielsen, Jens, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835739/
https://ncbi.nlm.nih.gov/pubmed/33478099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020348
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