Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19

PURPOSE: Host genetic variants may contribute to severity of COVID-19. NKG2C(+) NK cells are potent antiviral effector cells, potentially limiting the extent of SARS-CoV-2 infections. NKG2C is an activating NK cell receptor encoded by the KLRC2 gene, which binds to HLA-E on infected cells leading to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genet Med
Main Authors: Vietzen, Hannes, Zoufaly, Alexander, Traugott, Marianna, Aberle, Judith, Aberle, Stephan W., Puchhammer-Stöckl, Elisabeth
Format: Artigo
Sprog:Inglês
Udgivet: , The Author(s), under exclusive licence to the American College of Medical Genetics and Genomics 2021
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835668/
https://ncbi.nlm.nih.gov/pubmed/33500568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41436-020-01077-7
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker