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Mechanical allodynia triggered by cold exposure in mice with the Scn11a p.R222S mutation: a novel model of drug therapy for neuropathic pain related to Na(V)1.9

Mutations within the SCN11A gene which encodes the voltage-gated sodium channel Na(V)1.9 mainly expressed in small fiber sensory neurons have been associated with neuropathic disorders; however, suitable medications have not been fully investigated. To develop drug therapies against Na(V)1.9-related...

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Pubblicato in:Naunyn Schmiedebergs Arch Pharmacol
Autori principali: Matsubara, Yosuke, Okuda, Hiroko, Harada, Kouji H., Youssefian, Shohab, Koizumi, Akio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835175/
https://ncbi.nlm.nih.gov/pubmed/32970203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-020-01978-z
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