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Mechanical allodynia triggered by cold exposure in mice with the Scn11a p.R222S mutation: a novel model of drug therapy for neuropathic pain related to Na(V)1.9
Mutations within the SCN11A gene which encodes the voltage-gated sodium channel Na(V)1.9 mainly expressed in small fiber sensory neurons have been associated with neuropathic disorders; however, suitable medications have not been fully investigated. To develop drug therapies against Na(V)1.9-related...
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| Publicado no: | Naunyn Schmiedebergs Arch Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7835175/ https://ncbi.nlm.nih.gov/pubmed/32970203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-020-01978-z |
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