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Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein
There is increasing evidence that ACE2 gene polymorphism can modulate the interaction between ACE2 and the SARS-CoV-2 spike protein affecting the viral entry into the host cell, and/or contribute to lung and systemic damage in COVID-19. Here we used in silico molecular docking to predict the effects...
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| Publicado no: | Biochimie |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM).
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7834737/ https://ncbi.nlm.nih.gov/pubmed/33181224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2020.11.004 |
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