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High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity
A novel coronavirus (SARS-CoV-2) has emerged to a global pandemic and caused significant damages to public health. Human angiotensin-converting enzyme 2(ACE2) was identified as the entry receptor for SARS-CoV-2. As a carboxypeptidase, ACE2 cleaves many biological substrates besides Ang II to control...
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| Publicado no: | bioRxiv |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337377/ https://ncbi.nlm.nih.gov/pubmed/32637947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.01.182659 |
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