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Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin−ferroportin axis

Iron withholding, an essential component of nutritional immunity, plays a fundamental role in host resistance to Salmonella infection. Our previous study showed that SpvB, an important pSLT-encoded cytotoxic effector, facilitated Salmonella pathogenesis within macrophages via perturbing cellular iro...

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Détails bibliographiques
Publié dans:Gut Microbes
Auteurs principaux: Deng, Qifeng, Yang, Sidi, Sun, Lanqing, Dong, Kedi, Li, Yuanyuan, Wu, Shuyan, Huang, Rui
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833757/
https://ncbi.nlm.nih.gov/pubmed/33475464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2020.1849996
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