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Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, β(1)-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts
The role of prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR) was studied in an experimental model of wound healing in cultured fibroblasts. The cells were treated with PEPD (1–100 nM) and analysis of cell viability, proliferation, migration, collagen biosynthesis, PEPD act...
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Published in: | Int J Mol Sci |
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Main Authors: | , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
MDPI
2021
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7833428/ https://ncbi.nlm.nih.gov/pubmed/33477899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020942 |
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