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Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, β(1)-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts

The role of prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR) was studied in an experimental model of wound healing in cultured fibroblasts. The cells were treated with PEPD (1–100 nM) and analysis of cell viability, proliferation, migration, collagen biosynthesis, PEPD act...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Baszanowska, Weronika, Misiura, Magdalena, Oscilowska, Ilona, Palka, Jerzy, Miltyk, Wojciech
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833428/
https://ncbi.nlm.nih.gov/pubmed/33477899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020942
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