Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes

Recent reports have indicated prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR). Since this receptor is involved in the promotion of cell proliferation, growth, and migration, we aimed to investigate whether prolidase may participate in wound healing in vitro. All experimen...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Misiura, Magdalena, Baszanowska, Weronika, Ościłowska, Ilona, Pałka, Jerzy, Miltyk, Wojciech
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730528/
https://ncbi.nlm.nih.gov/pubmed/33287453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239243
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