Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can cause neurological disease in humans, but little is known about the pathogenesis of SARS-CoV-2 infection in the central nervous system (CNS). Herein, using K18-hACE2 mice, we demonstrate that SARS-CoV-2 neuroinvasion and ence...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Kumari, Pratima, Rothan, Hussin A., Natekar, Janhavi P., Stone, Shannon, Pathak, Heather, Strate, Philip G., Arora, Komal, Brinton, Margo A., Kumar, Mukesh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832889/
https://ncbi.nlm.nih.gov/pubmed/33477869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13010132
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