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Combination of Aptamer Amplifier and Antigen-Binding Fragment Probe as a Novel Strategy to Improve Detection Limit of Silicon Nanowire Field-Effect Transistor Immunosensors

Detecting proteins at low concentrations in high-ionic-strength conditions by silicon nanowire field-effect transistors (SiNWFETs) is severely hindered due to the weakened signal, primarily caused by screening effects. In this study, aptamer as a signal amplifier, which has already been reported by...

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Pubblicato in:Sensors (Basel)
Autori principali: Vu, Cao-An, Pan, Pin-Hsien, Yang, Yuh-Shyong, Chan, Hardy Wai-Hong, Kumada, Yoichi, Chen, Wen-Yih
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832338/
https://ncbi.nlm.nih.gov/pubmed/33477777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s21020650
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