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Synergetic improvements of sensitivity and specificity of nanowire field effect transistor gene chip by designing neutralized DNA as probe

Neutral DNA analogs as probes for the detection of target oligomers on the biosensors based on the field-effect transistor (FET) configuration feature advantages in the enhancement of sensitivity and signal-to-noise ratio. Herein, we used phosphate-methylated nucleotides to synthesize two partially...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Hu, Wen-Pin, Tsai, Chih-Chin, Yang, Yuh-Shyong, Chan, Hardy Wai-Hong, Chen, Wen-Yih
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105729/
https://ncbi.nlm.nih.gov/pubmed/30135473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30996-4
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