Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

Anthraquinones and their analogues, in particular heteroarene-fused anthracendiones, are prospective scaffolds for new compounds with improved antitumor characteristics. We herein report the use of a ‘scaffold hopping’ approach for the replacement of the core structure in the previously discovered h...

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Detaylı Bibliyografya
Yayımlandı:Eur J Med Chem
Asıl Yazarlar: Shchekotikhin, Andrey E., Dezhenkova, Lyubov G., Tsvetkov, Vladimir B., Luzikov, Yuri N., Volodina, Yulia L., Tatarskiy, Victor V., Kalinina, Anastasia A., Treshalin, Michael I., Treshalina, Helen M., Romanenko, Vladimir I., Kaluzhny, Dmitry N., Kubbutat, Michael, Schols, Dominique, Pommier, Yves, Shtil, Alexander A., Preobrazhenskaya, Maria N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832087/
https://ncbi.nlm.nih.gov/pubmed/26890118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.01.050
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