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Novel Mouse Model Recapitulates Genome and Transcriptome Alterations in Human Colorectal Carcinomas

Human colorectal carcinomas are defined by a nonrandom distribution of genomic imbalances that are characteristic for this disease. Often, these imbalances affect entire chromosomes. Understanding the role of these aneuploidies for carcinogenesis is of utmost importance. Currently, established trans...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Chromosomes Cancer
Hauptverfasser: McNeil, Nicole E., Padilla-Nash, Hesed M., Buishand, Floryne O., Hue, Yue, Ried, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832084/
https://ncbi.nlm.nih.gov/pubmed/27750367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22426
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