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Novel Mouse Model Recapitulates Genome and Transcriptome Alterations in Human Colorectal Carcinomas

Human colorectal carcinomas are defined by a nonrandom distribution of genomic imbalances that are characteristic for this disease. Often, these imbalances affect entire chromosomes. Understanding the role of these aneuploidies for carcinogenesis is of utmost importance. Currently, established trans...

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Detalles Bibliográficos
Publicado en:Genes Chromosomes Cancer
Main Authors: McNeil, Nicole E., Padilla-Nash, Hesed M., Buishand, Floryne O., Hue, Yue, Ried, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832084/
https://ncbi.nlm.nih.gov/pubmed/27750367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22426
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