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Simultaneous Activation of Erk1/2 and Akt Signaling is Critical for Formononetin-Induced Promotion of Endothelial Function

Formononetin (FMNT) is a major bioactive compound from Astragalus membranaceus (Fisch.) Bunge, and has been widely used to treat conditions related to vascular insufficiency. However, the molecular mechanism for the therapeutic effect has not been well defined. This study aimed to investigate the ef...

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Publicat a:Front Pharmacol
Autors principals: Wu, Jinjun, Kong, Muyan, Lou, Yanmei, Li, Leyan, Yang, Chunlin, Xu, Huifang, Cui, Yuqi, Hao, Hong, Liu, Zhenguo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832036/
https://ncbi.nlm.nih.gov/pubmed/33505313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.608518
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