Identification of MicroRNA-92a-3p as an Essential Regulator of Tubular Epithelial Cell Pyroptosis by Targeting Nrf1 via HO-1

Renal ischemia–reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) and has no effective treatment. Exploring the molecular mechanisms of renal IRI is critical for the prevention of AKI and its evolution to chronic kidney disease and end-stage renal disease. The aim of the present...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Wang, Renhe, Zhao, Haijun, Zhang, Yingyu, Zhu, Hai, Su, Qiuju, Qi, Haiyan, Deng, Jun, Xiao, Chengcheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831883/
https://ncbi.nlm.nih.gov/pubmed/33505436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.616947
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