CAR T cells in solid tumors: challenges and opportunities

BACKGROUND: CARs are simulated receptors containing an extracellular single-chain variable fragment (scFv), a transmembrane domain, as well as an intracellular region of immunoreceptor tyrosine-based activation motifs (ITAMs) in association with a co-stimulatory signal. MAIN BODY: Chimeric antigen r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Marofi, Faroogh, Motavalli, Roza, Safonov, Vladimir A., Thangavelu, Lakshmi, Yumashev, Alexei Valerievich, Alexander, Markov, Shomali, Navid, Chartrand, Max Stanley, Pathak, Yashwant, Jarahian, Mostafa, Izadi, Sepideh, Hassanzadeh, Ali, Shirafkan, Naghmeh, Tahmasebi, Safa, Khiavi, Farhad Motavalli
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831265/
https://ncbi.nlm.nih.gov/pubmed/33494834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02128-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker