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CAR T cells in solid tumors: challenges and opportunities
BACKGROUND: CARs are simulated receptors containing an extracellular single-chain variable fragment (scFv), a transmembrane domain, as well as an intracellular region of immunoreceptor tyrosine-based activation motifs (ITAMs) in association with a co-stimulatory signal. MAIN BODY: Chimeric antigen r...
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| Publicat a: | Stem Cell Res Ther |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7831265/ https://ncbi.nlm.nih.gov/pubmed/33494834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02128-1 |
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