A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT(2A) Receptor Density in the Pig Brain

A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT(2A)R) agonist, may be associated with antidepressant effects. The mechanism behind its antidepressive action is unknown but could be linked to increased synaptogenesis and down-regulation of cerebral 5-HT(2A)R. Here, we inves...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Raval, Nakul Ravi, Johansen, Annette, Donovan, Lene Lundgaard, Ros, Nídia Fernandez, Ozenne, Brice, Hansen, Hanne Demant, Knudsen, Gitte Moos
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830000/
https://ncbi.nlm.nih.gov/pubmed/33467676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020835
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