Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels

The main psychedelic component of magic mushrooms is psilocybin, which shows promise as a treatment for depression and other mental disorders. Psychedelic effects are believed to emerge through stimulation of serotonin 2A receptors (5-HT2ARs) by psilocybin’s active metabolite, psilocin. We here repo...

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Udgivet i:Neuropsychopharmacology
Main Authors: Madsen, Martin K., Fisher, Patrick M., Burmester, Daniel, Dyssegaard, Agnete, Stenbæk, Dea S., Kristiansen, Sara, Johansen, Sys S., Lehel, Sczabolz, Linnet, Kristian, Svarer, Claus, Erritzoe, David, Ozenne, Brice, Knudsen, Gitte M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785028/
https://ncbi.nlm.nih.gov/pubmed/30685771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0324-9
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