Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE((-/-)) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis

Aims/hypothesis: SGLT-2 inhibitors (SGLT-2i) have been studied as potential treatments against NAFLD, showing varying beneficial effects. The molecular mechanisms mediating these effects have not been fully clarified. Herein, we investigated the impact of empagliflozin on NAFLD, focusing particularl...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Nasiri-Ansari, Narjes, Nikolopoulou, Chrysa, Papoutsi, Katerina, Kyrou, Ioannis, Mantzoros, Christos S., Kyriakopoulos, Georgios, Chatzigeorgiou, Antonios, Kalotychou, Vassiliki, Randeva, Manpal S., Chatha, Kamaljit, Kontzoglou, Konstantinos, Kaltsas, Gregory, Papavassiliou, Athanasios G., Randeva, Harpal S., Kassi, Eva
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829901/
https://ncbi.nlm.nih.gov/pubmed/33467546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020818
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы