Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi

Chagas disease (CD) still represents a serious public health problem in Latin America, even after more than 100 years of its discovery. Clinical treatments (nifurtimox and benznidazole) are considered inadequate, especially because of undesirable side effects and low efficacy in the chronic stages o...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Lara, Leonardo S., Lechuga, Guilherme C., Moreira, Caroline dos S., Santos, Thaís B., Ferreira, Vitor F., da Rocha, David R., Pereira, Mirian C. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829778/
https://ncbi.nlm.nih.gov/pubmed/33467422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020423
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky