Suppression of Peritoneal Fibrosis by Sonoporation of Hepatocyte Growth Factor Gene-Encoding Plasmid DNA in Mice

Gene therapy is expected to be used for the treatment of peritoneal fibrosis, which is a serious problem associated with long-term peritoneal dialysis. Hepatocyte growth factor (HGF) is a well-known anti-fibrotic gene. We developed an ultrasound and nanobubble-mediated (sonoporation) gene transfecti...

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Veröffentlicht in:Pharmaceutics
Hauptverfasser: Nishimura, Koyo, Ogawa, Koki, Kawaguchi, Maho, Fumoto, Shintaro, Mukai, Hidefumi, Kawakami, Shigeru
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7829751/
https://ncbi.nlm.nih.gov/pubmed/33477422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13010115
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