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Inhibition of the Lipid Droplet–Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties

Cancer stem cells (CSCs), having both self-renewal and tumorigenic capacity, utilize an energy metabolism system different from that of non-CSCs. Lipid droplets (LDs) are organelles that store neutral lipids, including triacylglycerol. Previous studies demonstrated that LDs are formed and store lipi...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Kuramoto, Kenta, Yamamoto, Masahiro, Suzuki, Shuhei, Togashi, Keita, Sanomachi, Tomomi, Kitanaka, Chifumi, Okada, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828779/
https://ncbi.nlm.nih.gov/pubmed/33466690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12010099
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