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FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells

Cancer initiating cells (CICs) drive tumor formation and drug-resistance, but how they develop drug-resistance characteristics is not well understood. In this study, we demonstrate that chemotherapeutic agent FOLFOX, commonly used for drug-resistant/metastatic colorectal cancer (CRC) treatment, indu...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Ghatak, Shibnath, Hascall, Vincent C., Markwald, Roger R., Misra, Suniti
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828641/
https://ncbi.nlm.nih.gov/pubmed/33451103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020753
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