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Vitrification-induced activation of lysosomal cathepsin B perturbs spindle assembly checkpoint function in mouse oocytes

As the age of child-bearing increases and correlates with infertility, cryopreservation of female gametes is becoming common-place in ART. However, the developmental competence of vitrified oocytes has remained low. The underlying mechanisms responsible for reduced oocyte quality post-vitrification...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Balboula, Ahmed Z, Schindler, Karen, Kotani, Tomoya, Kawahara, Manabu, Takahashi, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828578/
https://ncbi.nlm.nih.gov/pubmed/32634244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaaa051
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