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Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL

Endothelial lipase (EL) is a strong modulator of the high-density lipoprotein (HDL) structure, composition, and function. Here, we examined the impact of EL on HDL paraoxonase 1 (PON1) content and arylesterase (AE) activity in vitro and in vivo. The incubation of HDL with EL-overexpressing HepG2 cel...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Schilcher, Irene, Stadler, Julia T., Lechleitner, Margarete, Hrzenjak, Andelko, Berghold, Andrea, Pregartner, Gudrun, Lhomme, Marie, Holzer, Michael, Korbelius, Melanie, Reichmann, Florian, Springer, Anna, Wadsack, Christian, Madl, Tobias, Kratky, Dagmar, Kontush, Anatol, Marsche, Gunther, Frank, Saša
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828365/
https://ncbi.nlm.nih.gov/pubmed/33450841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020719
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