Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL

Endothelial lipase (EL) is a strong modulator of the high-density lipoprotein (HDL) structure, composition, and function. Here, we examined the impact of EL on HDL paraoxonase 1 (PON1) content and arylesterase (AE) activity in vitro and in vivo. The incubation of HDL with EL-overexpressing HepG2 cel...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Schilcher, Irene, Stadler, Julia T., Lechleitner, Margarete, Hrzenjak, Andelko, Berghold, Andrea, Pregartner, Gudrun, Lhomme, Marie, Holzer, Michael, Korbelius, Melanie, Reichmann, Florian, Springer, Anna, Wadsack, Christian, Madl, Tobias, Kratky, Dagmar, Kontush, Anatol, Marsche, Gunther, Frank, Saša
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828365/
https://ncbi.nlm.nih.gov/pubmed/33450841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020719
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