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Control of Mesenchymal Stromal Cell Senescence by Tryptophan Metabolites

Cellular senescence contributes to aging and age-related disorders. High glucose (HG) induces mesenchymal stromal/stem cell (MSC) senescence, which hampers cell expansion and impairs MSC function. Intracellular HG triggers metabolic shift from aerobic glycolysis to oxidative phosphorylation, resulti...

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Foilsithe in:Int J Mol Sci
Príomhúdar: Wu, Kenneth K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828284/
https://ncbi.nlm.nih.gov/pubmed/33445766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020697
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