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Control of Mesenchymal Stromal Cell Senescence by Tryptophan Metabolites
Cellular senescence contributes to aging and age-related disorders. High glucose (HG) induces mesenchymal stromal/stem cell (MSC) senescence, which hampers cell expansion and impairs MSC function. Intracellular HG triggers metabolic shift from aerobic glycolysis to oxidative phosphorylation, resulti...
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| Pubblicato in: | Int J Mol Sci |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7828284/ https://ncbi.nlm.nih.gov/pubmed/33445766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020697 |
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