Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension

Treprostinil palmitil (TP) is a prodrug of treprostinil (TRE), a pulmonary vasodilator that has been previously formulated for inhaled administration via a nebulizer. TP demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonar...

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Publicado en:Int J Mol Sci
Main Authors: Plaunt, Adam J., Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R., Chapman, Richard W., Li, Zhili, Cipolla, David C., Perkins, Walter R., Malinin, Vladimir S.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828008/
https://ncbi.nlm.nih.gov/pubmed/33430435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020548
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